Treating Cardiovascular Disease Via Gene Therapy And The...

Topic: Discuss the technologies available for treating cardiovascular disease via gene therapy and the future direction of this as a therapeutic option. Introduction The definition of cardiovascular disease as stated by the British Heart Foundation is as follows, â€Å"cardiovascular disease includes all diseases of the heart and circulation, including coronary heart disease (i.e. angina, heart attack), heart failure, congenital heart disease, and stroke. It is also known as heart and circulatory disease.† Although there are numerous subtypes of cardiovascular disease they are all interrelated by a common setback. Atherosclerosis, which is the build-up of a fatty streak inside of the arterial walls, is the mutual element that links all forms of cardiovascular disease together. The build-up of fatty plaque inside of the artery walls can have a number of negative effects on the human body. For example, angina occurs when the narrowing of the arteries due to the build-up of plaque inhibits a sufficient amount of oxygen-rich blood to pass through to the heart. Similarly, a heart attack occurs when part of the fatty plaque breaks away or ruptur es and clots the coronary arteries, drastically reducing blood-supply to the heart. Both of these conditions lead to various side effects that can significantly lower ones quality of life or even result in death. The main risk factors that increase a persons chance of obtaining cardiovascular disease include smoking, obesity, highShow MoreRelatedMerck Case18783 Words   |  76 PagesPatrick Co-principal Project Investigators Center for International and Area Studies Yale University New Haven, CT 06520 203-432-9395 (Fax: 5963) e-mail: william.rapp@yale.edu Revised December 1998 Table of Contents 1. Introduction: Objective of this Study 2. The Pharmaceutical Industry in a Global Context 3. Product RD and Clinical Trials 4. Manufacturing and Process RD 5. Technological Factors Structure-Based Drug (Rational Drug) Design Structure-Based Drug (Rational Drug) Design 6. MerckRead MoreMergers Acquisitions in Pharma Industry21425 Words   |  86 Pages ABSTRACT One plus one makes three. This is the special alchemy of Merger and Acquisitions. When two firms, often about the same size, agree to go forward as a new single company rather than remain separately owned and operated, a merger happens. Mergers facilitate synergies between the merged companies, generate efficiency, competitiveness, and increase the economies of scale, spreading costs, acquiring new technology over a large customer base. By this Research paper I have attempted implicationsRead MoreDeveloping Management Skills404131 Words   |  1617 Pages10/12 Weidemann-Book Credits and acknowledgments borrowed from other sources and reproduced, with permission, in this textbook appear on appropriate page within text. Copyright  © 2011, 2007, 2005, 2002, 1998 Pearson Education, Inc., publishing as Prentice Hall, One Lake Street, Upper Saddle River, New Jersey 07458. All rights reserved. Manufactured in the United States of America. This publication is protected by Copyright, and permission should be obtained from the publisher prior to any prohibitedRead More_x000C_Introduction to Statistics and Data Analysis355457 Words   |  1422 PagesIntroduction to Statistics and Data Analysis This page intentionally left blank Introduction to Statistics and Data Analysis Third Edition Roxy Peck California Polytechnic State University, San Luis Obispo Chris Olsen George Washington High School, Cedar Rapids, IA Jay Devore California Polytechnic State University, San Luis Obispo Australia †¢ Brazil †¢ Canada †¢ Mexico †¢ Singapore †¢ Spain †¢ United Kingdom †¢ United States Introduction to Statistics and Data Analysis, Third